The PSMB1 Antibody (C-term) from MyBioSource.com is a Rabbit Polyclonal antibody to PMSB1, and PSMB1. This antibody recognizes Human, and Mouse antigen. The PSMB1 Antibody (C-term) has been validated for the following applications: ELISA, Flow Cytometry, Immunofluorescence, Immunohistochemistry, and Western Blot.
Description
PSMB1 is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides